Robyn L. Tanguay
Distinguished Professor | Department of Environmental and Molecular Toxicology
Director of Superfund Research Program
Director of Environmental Health Sciences Center
Director of Sinnhuber Aquatic Research Laboratory
Robyn Leigh Tanguay (Formerly Robert Leonard Tanguay) is a Distinguished Professor in the Department of Environmental and Molecular Toxicology, the Director of the Oregon State University Superfund Research Program, Director of the Sinnhuber Aquatic Research Laboratory, and the Director of an Environmental Health Sciences Center. She received her BA in Biology from California State University-San Bernardino, her PhD in Biochemistry from the University of California-Riverside and postdoctoral training in Developmental Toxicology from the University of Wisconsin-Madison. She serves on a number of academic, commercial and federal advisory boards and is on the editorial board for several scientific journals. Over the past several years she has pioneered the use of zebrafish as a toxicology model and recently developed automated high throughput instrumentation to accelerate phenotype discovery in zebrafish. A major focus in on identifying chemicals and mixtures that produce neurotoxicity. Phenotypic anchoring coupled with the inherent molecular and genetic advantages of zebrafish are used to define the mechanisms by which chemicals, drugs and nanoparticles interact with and adversely affect vertebrate development and function.
Assistant Professor (Sr. Research)
Deputy Director of Sinnhuber Aquatic Research Laboratory
Lisa Truong is currently an Assistant Professor in the Department of Environmental and Molecular Toxicology, and the Deputy Director of the Sinnhuber Aquatic Research Laboratory at Oregon State University, where her research program goal is to utilize the zebrafish model to build computational models to be less reliant on animal testing and conduct toxicity-testing based on toxicity pathways. She received her Ph.D. in Toxicology at Oregon State in 2012 which focused on identifying the structure-activity relation of nanoparticles in the zebrafish model and was a postdoctoral fellow at US EPA-National Center for Computational Toxicology from 2012-2014. Lisa has been conducting research in the nanotoxicology and high throughput screening using zebrafish for the last 10 years. Dr. Truong is author/co-author of over 40 publications and has mentored over a dozen students.
Jane La Du
Since receiving a B.S. in Zoology at OSU in 2003, I have been an FRA and lab manager in the Tanguay lab. In addition to assisting graduate, undergraduate and visiting students in their studies, my main research interests have focused on investigating the role of population genetic variation that results in differential susceptibility to chemical exposure, and characterization of a novel long non-coding RNA activated following TCDD exposure.
Eric Johnson, MS
SARL Facility Manager
Michael Simonich, PhD
High Throughput Screening Director
Mike works in all aspects of developmental toxicity testing at the SARL and contributes experience in molecular biology and technical writing.
Lindsey St. Mary, PhD
Post Doctoral Fellow
I am currently an NIEHS postdoctoral trainee at the Tanguay Lab assessing toxicity of 9,000 representative chemicals found in consumer products. I received my Bachelor of Science degree at Oregon State University in General Science, Pre-vet and then went on to North Carolina State University where I received my master’s in Toxicology. My PhD training and research was done in Edinburgh, Scotland at Heriot-Watt University where I investigated time-related alteration of bioactive polycyclic aromatic hydrocarbon (PAH) photoproducts in the presence of TiO2 nanoparticles. My previous research has included investigations of iAs-mediated immunosupression, toxicity of high-nitrogen compounds, nitrates/nitrites, smoke dyes, various nanoparticles, and other environmental pollutants which involved the use of diverse molecular and analytical chemistry techniques. I spend most of my spare time exploring Oregon with my dog, Lilly, and enjoy craft cider, lifting weights, and alien podcasts 🙂
Subham Dasgupta, PhD
Post Doctoral Fellow
I am a molecular toxicologist, working as a postdoctoral fellow within Dr. Robyn Tanguay’s lab at the Sinnhuber Aquatic Research Laboratory, Oregon State University. I got my BS in Human Physiology (2008) and MS in Environmental Science (2010) from the University of Calcutta, India. Following this, I got my PhD (2016) from the School of Marine and Atmospheric Sciences, Stony Brook University, NY, where I was mentored by Dr. Anne McElroy. As my PhD dissertation, I partook a multistressor approach to study the ecotoxicological impacts of the Deepwater Horizon Oil spill and assessed the combinatory role of crude and dispersed oil, oil spill dispersants and hypoxia in driving CYP1A perturbation, genotoxicity and oxidative stress in developing fish (sheepshead minnow) and cell line (rainbow trout liver/ RTL-W1). Following this, I worked as a postdoc in Dr. David Volz’s lab at University of California, Riverside (2017-2019), where I used zebrafish as a model to understand the developmental toxicity of organophosphate flame retardants and PFASs, anchoring phenotyping observations to multi-omic responses. In 2019, I joined Dr. Tanguay’s lab and am currently using zebrafish as a model to- 1) understand the molecular basis of the role of a AhR-dependent long non-coding RNA (slincR) on embryonic development, 2) systemically assess phenotypic and molecular responses of 5G-level radiofrequency radiations and 3) understand systems level effects of flame retardants.
Post Doctoral Fellow
Dr. Delia Shelton is a National Science Foundation Postdoctoral Fellow in Biology. She received her BS in Animal Behavior and Spanish at Southwestern University, a teaching certificate from Prairie View A&M University and a dual PhD in Psychological and Brain Sciences and Evolution, Ecology and Behavior from Indiana University. She studies how environmental features influence social behavior in wild and domestic zebrafish. Shelton uses a combination behavioral assays, social network analyses, physiological manipulations and toxicological exposures to examine how pollutants directly and indirectly disrupt social behavior. She also has a vested interest in developing high-throughput phenotyping assays to screen zebrafish and other models.
I am a third year PhD student in the Department of Environmental and Molecular Toxicology. I earned a B.S. in Biology from St. John’s University in New York, along with minors in Chemistry and Environmental Studies. After graduating, I worked as a biological fieldwork technician for the Oregon Department of Fish and Wildlife and as a laboratory technician at The Clorox Company before coming to OSU. Currently, I am investigating the toxicity of per- and polyfluoroalkyl substances (PFAS) using zebrafish as a model, working to elucidate structure-bioactivity relationships and explore modes of action. Outside of the lab, I enjoy hiking and running with my dogs, playing sports, and baking.
I am a third year PhD student in Environmental and Molecular Toxicology. I graduated with a dual-degree B.S. in Biology and Environmental Science from Doane University (Nebraska) in 2015 and my research background is in ecology and sustainable agriculture. My current research interests focus on investigating molecular mechanisms of toxicity of polycyclic aromatic hydrocarbons in zebrafish using transcriptomics, epigenetics, and mutant fish lines.
Christian hails from Redding, California and received his BS in Chemistry at Pacific Lutheran University in 2017. As an undergrad he developed an SPME-GCMS method for investigating migration of residual acrylonitrile from plastic cups into hot chocolate. After graduating he meandered through a variety of work roles including youth ministry, substitute teaching, medical scribing, and quality control for a mint flavoring company. A newly established Tanguay lab member, he is excited to use the zebrafish model to better understand mechanisms underlying PAH toxicity.
Christopher M. Sullivan
I have been working in the field of computational science for 18 years and currently has over 30 co-authored scientific publications. My work has focused on Biocomputing and life sciences that change the way we look at and interact with the environment. Over the years I have worked endlessly to remove any computational limits that change the scope of work we can do or introduces a bias to a research question. I am currently the Assistant Director for Biocomputing in the Center for Genome Research and Biocomputing at Oregon State. In this position at the CGRB I work with 26 departments of research faculty doing research on everything from identification of plankton in our oceans to assembly of genomes and much more. This viewpoint provides a unique opportunity to find and remove limits effecting all research computing
My research is focused on understanding toxicity of PFAS, and developing Zebrafish behavior assays
EARLY CAREER SCIENTISTS
I’m a fourth year undergraduate student with a major in animal science and a minor in chemistry. I hope my next stop is veterinary school where I want to focus on large animal medicine, animal welfare, and how it connects to our environment.
Since graduating from OSU in 2019 with a B.S. in Microbiology and minor in Chemistry, I’ve been working at the Tanguay Lab assisting with various genotyping, behavioral, and embryo screening projects.
Special assistant to Dr. Truong
I’m a 3nd year undergraduate student with a B.A in psychology. I hope to pursue emergency medicine after I graduate. I enjoy caring for my large collection of house plants and hanging out with my dog, Cerberus.